منابع مشابه
Gut Immunity: A NOD to the Commensals
The gut microbiota play critical roles in intestinal function, but the mechanisms involved remain obscure. Recent studies suggest that commensal bacteria promote immune homeostasis via the innate immune receptor Nod1.
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The gut microbiota is an important contributor to host health and fitness. Given its importance, microbiota composition should not be left to chance. However, what determines this composition is far from clear, with results supporting contributions of both environmental factors and host genetics. To gauge the relative contributions of host genetics and environment, specifically the microbial di...
متن کاملYeasts in the gut: from commensals to infectious agents.
BACKGROUND Controversy still surrounds the question whether yeasts found in the gut are causally related to disease, constitute a health hazard, or require treatment. METHODS The authors present the state of knowledge in this area on the basis of a selective review of articles retrieved by a PubMed search from 2005 onward. The therapeutic recommendations follow the current national and intern...
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Detailed studies of the chickenmicrobiome have emerged in recent years, largely due to the impact of next-generation sequencing (NGS). We increasingly understand how the microbiome is important in health, in development of the gut and the immune system, and in maintenance of homeostasis. Manipulation of the microbiota directly through probiotics or antimicrobials or indirectly through feed and ...
متن کاملGut reaction
The image above shows immunofluorescence staining of a cross-section of small intestine from a mouse with a 'mosaic' pattern of expression of cell-surface MHC (major histocompatibility complex) class I molecules. The mosaic effect can be seen on the intestinal villi, which contain stretches of epithelial cells that express MHC class I (bright green) interrupted by equally long stretches of cell...
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ژورنال
عنوان ژورنال: Science
سال: 2020
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.368.6494.962-c